How Does EFUDEX Work?

AK and BCC lesions multiply at a faster rate than normal cells. Fluorouracil, the active ingredient in EFUDEX, is believed to interfere with a cell's ability to reproduce. As a result, the unhealthy cells absorb the fluorouracil in EFUDEX faster than healthy, normal cells.

What Can I Expect During Treatment?

During the first 2 to 4 weeks of treatment, the areas of your skin affected by AK or BCC lesions will probably turn red and look and feel irritated. This is typical and should not cause concern. The redness, crusting, and peeling are signs that EFUDEX is working to eliminate the unhealthy cells. Even though this stage of treatment may be unattractive and somewhat uncomfortable, it is important that you do not stop the therapy.

Some patients may be concerned with the inflammation associated with EFUDEX therapy. Talk to your doctor; he or she can best assess the situation and advise you.

Areas of your skin where there were no lesions may become red and inflamed. This is because abnormal cells can become inflamed even if the cells were not previously noticeable on the skin's surface. The more AKs you have, the more redness and inflammation you can expect during treatment.

How do I use EFUDEX?

EFUDEX Cream: Apply it to the affected areas once a day - preferably in the evening. Use enough cream to cover the lesions, and be careful when applying near the eyes, nose, and mouth.

You may apply EFUDEX Cream with a nonmetal applicator, a suitable glove, or your fingertips. Be sure to wash your hands thoroughly after each application.

How can I tell the difference between a normal reaction to EFUDEX and an allergic reaction?

Itching, burning, soreness, tenderness, scaling, and swelling are common reactions to EFUDEX therapy. An allergic reaction should be suspected when a patient complains of marked itching and discomfort. If you are concerned about the side effects you're experiencing, talk to your doctor. He or she can best assess the situation and more fully answer your questions.

I noticed some spots on my legs that I forgot to show Dr B. Can I use EFUDEX there, too?

Only your doctor can determine if the "spots" you have are AKs or BCCs and can be treated with EFUDEX. This is why it is so important to use EFUDEX only as directed and discuss any questions you may have with your doctor.

Can I use cosmetics or other skin products while using EFUDEX?

Patients are advised not to use cosmetics or any other skin products, including creams, lotions, and medications, while on EFUDEX therapy unless instructed by their doctor.

Should I avoid the sun while using EFUDEX?

During EFUDEX treatment, you should do everything possible to stay out of the sun. However, with an active lifestyle, this isn't always possible. So be sure you take every precaution to protect your skin. Wear long sleeves and a hat when you go outside, and ask your doctors about the use of sunscreen on areas that aren't covered by clothing.

What should I do if I forget an application of EFUDEX?

Simply resume using it as prescribed by your doctor. Do not increase or double your dose.

Are there people who should not use EFUDEX?

EFUDEX should not be used in women who are or may become pregnant during therapy because it may cause harm to the fetus. If you are nursing, be sure to let your doctor know because it is not known whether EFUDEX is excreted in human milk. Also, EFUDEX should not be used by people who are known to be allergic to any of its components.

What kind of follow-up care Is needed?

You should visit your doctor after therapy to plan your follow-up care, including regular appointments to make sure new lesions are not developing.

What should I do with any EFUDEX that is left over after I complete therapy?

Discard any unused portion of EFUDEX after you have completed therapy.

Of course, if you still have any other questions about EFUDEX, please call our office at:
973-635-5050